Large-Part Machining is here defined as the challenge of machining any part that is too heavy or bulky for a single human being to move the part to another location quickly, or too large to fit within the work zone of the most commonly available CNC machine tools. Parts such as these could apply to almost any industry, though aircraft, construction, power generation, and oil drilling are ready examples of industries that commonly have a need for very large machined parts. In large-part machining, much of the challenge has to do with performing as much of the work as possible in a single setup. Five-axis or 3+2 machining is often required to let a machining center reach many of the features of the part in a single setup. On-machine probing is another important resource, because the machine is often required to precisely locate the part prior to machining and may even inspect the part after machining is done.